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For U.S. residents only.
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Symptoms & Diagnosis
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 Symptoms
Chemicals released by mast cells cause changes in your body’s functioning. These can lead to typical allergic responses such as flushing, itching, abdominal cramping, and even shock. When too many mast cells are in your body, the additional chemicals can cause: It can also cause episodes of hypotension (very low blood pressure and faintness) or anaphylaxis (shock). Diagnosis The diagnosis of systemic mastocytosis is made when an increased number of abnormal mast cells is found during an examination of your bone marrow. Other tests that are important in evaluating a suspected case of mastocytosis include measurement of a protein (tryptase) from mast cells in your blood and a search for specific genetic mutations that health experts associate with this disease. Novartis Oncology is conducting clinical research to determine if the study drug midostaurin is safe and effective in people who have either aggressive systemic mastocytosis (ASM) or mast cell leukemia (MCL). If you are a US resident and would like to see if you may qualify to participate in this study, click on the button below.
If you are not an US resident please, click here to visit the ClinicalTrials.gov website for information on other participating countries. [Source: National Institute of Allergy and Infectious Diseases (NIAID); http://www.niaid.nih.gov.]
To view all Novartis clinical trials recruiting in the U.S., visit NovartisClinicalTrials.com |
