Study Description
Screening
Study Centers
Contact/Consent
Multiple Myeloma
Multiple myeloma is cancer that begins in plasma cells, a type of white blood cell. Plasma cells are white blood cells that make antibodies. Antibodies are part of the immune system. They work with other parts of the immune system to help protect the body from germs and other harmful substances. [Source: www.cancer.gov]
Novartis is seeking people to participate in a clinical trial(s) testing the safety
and effectiveness of Novartis products. Novartis recommends that you consult your
doctor before participating in a clinical trial.
How to use this system:
The purpose of this system is to help connect interested study participants with clinical
research centers. The following is a brief outline explaining the main steps involved in
using this system. Please note that every step in this process is optional.
1. Select a clinical trial that you feel best suits your (or the participant's)
health condition.
2. Answer the screening questions to see if you (or the participant) meet
the preliminary qualifications for
the study. The answers to these questions
are not retained by this system.
3. Select a study center to contact for additional information about the
clinical trial.
4. Set up an account and agree to the terms of use for this system.
5. Submit your information to the study center you selected.
6. The study center may contact you and may ask more questions about your
(or the participant's) eligibility
for the study. The study center may invite you
(and the participant if applicable) to travel to the study center
for additional screening tests. Novartis cannot guarantee that you
will be contacted by the study center.
7. If you are eligible to participate in the study, then you will be required
to sign an
informed consent before enrolling in the study. An informed consent
is provided to you to help you understand the clinical trial, the nature of
the medical treatment (if any),
procedures and known risks involved, before you agree to participate in the study.
For more information about clinical trial participation, click here. Also, for additional information
about how Novartis helps to protect the privacy of the personal information that you provide to us, please
see the Novartis Privacy Policy.
Please review the details of the clinical trial(s) listed below and click on the one that you feel best suits
your (or the participant's) condition.
Multiple Myeloma Study CLBH589B2206
The purpose of this clinical trial is to find out the effects, both positive and negative, of a study drug called LBH589 when administered together with oral lenalidomide and dexamethasone to people who have a form of bone marrow cancer called Multiple Myeloma that has not responded to prior treatments. The study drug LBH589 is being tested as part of this study and is currently not available for purchase on the market in any country.
Trial phase: Phase 1
Participation Duration: Participants will be required to take 3 drugs over a 28 day period. They will take oral LBH589 once-a-day on Monday, Wednesday, and Friday each week. In addition, they will take lenalidomide once-a-day, and dexamethasone once-a-day on specific days during the 28 day treatment cycle. Participants will be asked to come to the clinic one to four times each week. Each of these visits should take about 1-3 hours, but there are a few visits that may take up to 8 hours.
Protocol Number: CLBH589B2206
Multiple Myeloma Study CLBH589B2207
The purpose of this clinical trial is to find out the effects, both positive and negative, of a study drug called LBH589 when administered together with bortezomib to people who have a form of bone marrow cancer called Multiple Myeloma that has not responded to prior treatments. The study drug LBH589 is being tested as part of this study and is currently not available for purchase on the market in any country.
Trial phase: Phase 1
Participation Duration: Participants will take oral LBH589 once-a-day on Monday, Wednesday, and Friday each week. In addition, participants will receive an injection of bortezomib twice weekly for 2 weeks. Participants will be asked to come to the clinic for five visits in the first week of the study, with the frequency of visits reducing thereafter for the length of participation in the study. Each of these visits should take about 1-3 hours, but there are a few visits that may take up to 8 hours.
Protocol Number: CLBH589B2207
|