The purpose of this clinical trial is to compare the two drugs pasireotide LAR and octreotide LAR to find out which of these medicines gives the best relief from the diarrhea and flushing symptoms in participants with carcinoid disease who are not responding to other drugs. Pasireotide is a new medicine which has not yet been approved by Health Authorities and therefore it is not currently available for sale in any country. Octreotide has been approved by Health Authorities and is available for sale, however, the dose to be used in this study, 40 mg, has not been approved by Health Authorities for sale.
Trial phase: Phase 3
Participation Duration: Participants will be asked to visit the study site 10 times over about 10 months. Each visit should take about 2 hours. During the first month, participants will be required to make 3 visits, and then one visit per month thereafter. At the end of the study, participants will have an option to continue the study (in the extension portion) for another 24 months.
Protocol Number: Carcinoid Tumors Study CSOM230C2303