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Chronic Obstructive Pulmonary Disease (COPD)

Two major diseases contribute to COPD: emphysema and chronic bronchitis. The chief symptoms are chronic cough, spitting or coughing up mucus (expectoration), breathlessness on exertion, and progressive reduction in the ability to breathe out fully. Cigarette smoking accounts for 82% of COPD deaths.

Novartis is seeking people to participate in a clinical trial(s) testing the safety and effectiveness of Novartis products. Novartis recommends that you consult your doctor before participating in a clinical trial.

How to use this system:

The purpose of this system is to help connect interested study participants with clinical research centers. The following is a brief outline explaining the main steps involved in using this system. Please note that every step in this process is optional.

1. Select a clinical trial that you feel best suits your (or the      participant's) health condition.
2. Answer the screening questions to see if you (or the      participant) meet the preliminary qualifications for the study.      The answers to these questions are not retained by this      system.
3. Select a study center to contact for additional information      about the clinical trial.
4. Set up an account and agree to the terms of use for this      system.
5. Submit your information to the study center you selected.
6. The study center may contact you and may ask more      questions about your (or the participant's) eligibility for the      study. The study center may invite you (and the participant if      applicable) to travel to the study center for additional screening      tests. Novartis cannot guarantee that you will be contacted by      the study center.
7. If you are eligible to participate in the study, then you will be      required to sign an informed consent before enrolling in the      study. An informed consent is provided to you to help you      understand the clinical trial, the nature of the medical treatment      (if any), procedures and known risks involved, before you agree      to participate in the study.

For more information about clinical trial participation, click here. Also, for additional information about how Novartis helps to protect the privacy of the personal information that you provide to us, please see the Novartis Privacy Policy.

Please review the details of the clinical trial(s) listed below and click on the one that you feel best suits your (or the participant's) condition.

Chronic Obstructive Pulmonary Disease Study CACZ885B2204

The purpose of this clinical research study is to compare multiple increasing doses of an intravenous (iv) investigational drug to determine if it is safe and effective for participants with moderate to severe Chronic Obstructive Pulmonary Disease (also known as COPD) and are between the ages of 40 and 75 years old. An “investigational drug” is a drug that is being tested and is not approved for sale in the United States by the U.S. Food and Drug Administration (FDA).
Trial phase: Phase 2
Participation Duration: Participants will receive a total of 13 intravenous (IV) infusions (directly into the vein) of the investigational drug over a period of 45 weeks. There will be a 12 week follow-up period where there will be no drug administered. The total duration of the study is 57 weeks.
Protocol Number: CACZ885B2204

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Chronic Obstructive Pulmonary Disease (COPD)